My main scientific interest is bacterial cooperation under oxidative stress, trying to understand how bacterial
populations work together to survive the neutrophil oxidative burst.
I initially studied Biochemistry at the University of Oxford, where I did my master's in the Uphoff group working on the population density dependence of H202 tolerance in E. coli. During this time I worked on how survival is driven both by the intracellular biochemistry of the stress response, and intercellular interactions within a population.
I then joined the LCB to start my PhD in 2024 as part of the Bansept and Ezraty groups, aiming to investigate this interface between intra- and intercellular processes further. My project is focussed specifically on less well studied neutrophil-derived stresses, using Salmonella as a model organism. My focus is on using quantitative fluorescence microscopy paired with microfluidics to track gene regulatory and morphological dynamics at both single cell and population levels over time. We can use this data to construct models, which we can use to further understand the processes which allow Salmonella to resist the oxidative stresses of the immune system.
I initially studied Biochemistry at the University of Oxford, where I did my master's in the Uphoff group working on the population density dependence of H202 tolerance in E. coli. During this time I worked on how survival is driven both by the intracellular biochemistry of the stress response, and intercellular interactions within a population.
I then joined the LCB to start my PhD in 2024 as part of the Bansept and Ezraty groups, aiming to investigate this interface between intra- and intercellular processes further. My project is focussed specifically on less well studied neutrophil-derived stresses, using Salmonella as a model organism. My focus is on using quantitative fluorescence microscopy paired with microfluidics to track gene regulatory and morphological dynamics at both single cell and population levels over time. We can use this data to construct models, which we can use to further understand the processes which allow Salmonella to resist the oxidative stresses of the immune system.
